Study “Confirms That The Full Degree Of Harm Of Antidepressants Is Not Reported”

Quote

 

The Facts: Multiple studies outlined in this article indicate a serious issue with the efficacy of antidepressant drugs, and the lengths that pharmaceutical companies go to hide potential dangers. Reflect On: How much science is there really behind the efficacy of antidepressant drugs?

A study published in the British Medical Journal by researchers at the Nordic Cochrane Center in Copenhagen showed that pharmaceutical companies were not disclosing all information regarding the results of their drug trials. Researchers looked at documents from 70 different double-blind, placebo-controlled trials of selective serotonin reuptake inhibitors (SSRI) and serotonin and norepinephrine reuptake inhibitors (SNRI) and found that the full extent of serious harm in clinical study reports went unreported. These are the reports sent to major health authorities like the U.S. Food and Drug Administration.

study published in the British Medical Journal  by researchers at the Nordic Cochrane Center in Copenhagen showed that pharmaceutical companies were not disclosing all information regarding the results of their drug trials. Researchers looked at documents from 70 different double-blind, placebo-controlled trials of selective serotonin reuptake inhibitors (SSRI) and serotonin and norepinephrine reuptake inhibitors (SNRI) and found that the full extent of serious harm in clinical study reports went unreported. These are the reports sent to major health authorities like the U.S. Food and Drug Administration.

Tarang Sharma, a PhD student at Cochrane and lead author of the study, said:

We found that a lot of the appendices were often only available upon request to the authorities, and the authorities had never requested them. I’m actually kind of scared about how bad the actual situation would be if we had the complete data. (source)

Due to problems with selective reporting, even within CSRs, raw data from clinical drug trials should be preferred when conducting systematic reviews, with CSRs being the next-best option. As SSRIs and SNRIs can have very serious detrimental effects on children and adolescents, far more than previously noted, their use in young people should be reconsidered. In fact, even when considering all ages, placebo seems to be a better pill than an antidepressant drug because the patients weigh the benefits against the harms when they decide whether to stay in a trial or to drop out. (source)

Joanna Moncrieff, a psychiatrist and researcher at University College London, elaborates:

This study confirms that the full degree of harm of antidepressants is not reported. They are not reported in the published literature, we know that – and it appears that they are not properly reported in clinical study reports that go to the regulators and from the basis of decisions about licensing. (source)

Peter Gotzsche, a clinician researcher at Cochrane and the co-author of the study, actually tried to gain access to clinical trial reports almost a decade ago for anti-obesity pills. Unfortunately, the European Medicines Agency (EMA) denied them the reports:

They talked about commercial confidentiality although there was absolutely nothing in these reports that was commercially confidential. We explained that all this secrecy actually cost human lives, but they weren’t interested in that at all. (source)

It took years of requests and complaints for this to happen and, while Gotzsche is pleased they were able to achieve this breakthrough, he reminds us that similar progress has yet to made in the United States. He went on to state that researchers need better access to data from clinical trials to conduct assessments unimpeded by industry influence:

[…]

We really don’t have good enough evidence that antidepressants are effective and we have increasing evidence that they can be harmful. So we need to go into reverse and stop this increasing trend of prescribing [them]. (source)

One of the latest studies published on the subjects titled “Should antidepressants be used for major depressive disorder” published in the British Medical Journal states,

The benefits of antidepressants seem to be minimal and possibly without any importance to the average patient with major depressive disorder. Antidepressants should not be used for adults with major depressive disorder before valid evidence has shown that the potential beneficial effects outweigh the harmful effects.

[…]

Article Source

via Study “Confirms That The Full Degree Of Harm Of Antidepressants Is Not Reported” — NationalAddictionNews.com

New Report Reveals Goldman Sachs’ Crime Wave Under Last Three CEOs (Who Got Obscenely Rich in the Process)

Quote

The pattern of illegal conduct has actually increased since the 2008 crash.

By Pam Martens and Russ Martens of Wall Street on Parade.

 

Yesterday, the nonprofit Wall Street watchdog, Better Markets, released an in-depth and scathing analysis of the past 20 years at Goldman Sachs. A bold headline summed it up as follows: “$874 Billion in Bailouts, 36 Major Legal Actions,
$9.8 Billion in Fines and Settlements with Billions More Coming.”
 
One key takeaway from this crime spree, write the authors, is this:

“Goldman Sachs has amassed a RAP sheet showing that the financial crash of 2008 did little if anything to slow the pace of illegal activity that was well underway in the years leading up to the crash. Goldman Sachs was heavily engaged in illegal activity before the crash; they reached new heights of lawlessness in connection with the crash; and they continued to violate the law in the post-crash era….”

Senator Bernie Sanders has repeatedly stated that the business model of Wall Street is fraud. We’ve refined that to the business model of Wall Street is monetizing fraud. And based on this latest report, Goldman Sachs takes the top prize for its panoply of innovations in monetizing fraud.

The Better Markets report raises serious concerns on multiple fronts. First, it traces the Goldman Sachs’ crime wave from 1998 through 2019. Three separate CEO’s served during that period, all of whom became obscenely rich and none of whom curbed the crime wave. Despite all of the federal and state investigations that arose as a result of the Wall Street corruption that brought on the crash of 2008, the report found that the pattern of illegal conduct actually increased at Goldman Sachs after the 2008 crash […]

via New Report Reveals Goldman Sachs’ Crime Wave Under Last Three CEOs (Who Got Obscenely Rich in the Process) — Rigged Game

Americans Keep Putting Up Roadblocks Against Russian Troops on Key Syrian Highway

Quote

By Marko Marjanović | Anti-Empire | January 29, 2020

This is now the fourth time this has happened that we know of. US troops in northeastern Syria keep blockading the M4 highway to prevent Russian troops from moving on it.

In fall of 2019, to prevent a Turkish invasion of the Kurdish-held northeastern Syria, the Pentagon hammered out a deal with the Turks for joint US-Turkish patrols on the Syrian side of the Syrian-Turkish border.

As soon as that happened however Trump, after a talk with Erdogan, declared and ordered a US military withdrawal from Syria. At this moment Russia jumped in and took over the US role in the formerly US-Turkish agreement. To minimally appease Erdogan and limit his invasion it would now be Russians who patrolled together with the Turks, which was welcomed by the Kurdish leadership.

In separate negotiations with the Kurds the Russians also gained a number of bases in the northeast to make the patrols possible, and thousands of Syrian army troops also poured in to reinforce the Kurds against the Turkish invasion in the limited sector it was taking place in.

At this point Trump reversed himself, saying US forces would stay in Syria, but only in the oil-rich parts. But the withdrawal from the Syrian-Turkish border, where US presence had hampered US-Turkish relations, would be permanent.

Blue is the obvious path, but the Americans insist the Russians must hug the border along the red path

What is happening now is that when the Russians coming from the west want to take the direct and obvious route to their facilities in the city of Qamishli they periodically encounter US troops near the town of Tell Tamr standing in their way.

The Americans block the road with their vehicles and demand the Russians take the longer, indirect way to Qamishli along inferior roads hugging the Syrian-Turkish border.

via Americans Keep Putting Up Roadblocks Against Russian Troops on Key Syrian Highway

Then & Now: Portugal’s Drug Decriminalization

Quote

By Tyler Durden – Zero Hedge – 01/29/2020

During the 1990s, Portugal was devastated by a drug crisis where one in every 100 people became addicted to heroin and the rate of HIV infection soared to become the highest in the European Union.

But, as Statista’s Niall McCarthy notes, Portugal’s radical move to put an end to the carnage should prove an example to other countries dealing with similar problems, especially the United States where opioids have killed more people than the totality of American military casualties in Vietnam, both Iraq wars and Afghanistan combined.

That move was decriminalizing the consumption of all drugs and Portugal became the first country to do it.

The policy saw the status of using or possessing drugs for personal use remain illegal. However, offenses were changed from being criminal in nature which involved prison as a possible punishment to being administrative if the amount possessed was no more than a ten-day supply. Needle exchange programs have also been in place since 1993 and today, all drug users can exchange syringes at pharmacy counters across Portugal. Drug treatment was also expanded and improved with successful results.

Finding historical data highlighting the severity of the addiction problem during the late 1990s is difficult but some important numbers do exist which help to show just how remarkable Portugal’s recovery has been. The following infographic pulls data together from several sources to illustrate some key developments.

You will find more infographics at Statista

 

via Then & Now: Portugal’s Drug Decriminalization

US At Risk of Ecological Disaster Due to Improperly Stored Nuclear Waste, New Study Finds

Quote

Sputnik – January 29, 2020

The United States does not currently have a landfill for nuclear waste from the defense industry, which is normally stored inside metal canisters buried underground near the nuclear plants where it was produced.

The United States could face the risk of nuclear contamination due to inadequate nuclear waste storage methods, a new publication in the journal Nature Materials revealed.

According to the lead scientist behind the research, Xiaolei Guo, the existing techniques are insufficient to keep waste stored safely, as the material used in the current storage methods quickly becomes corroded, raising the risk of nuclear waste leaking into the soil, water and air.

The research team carried out an experiment in simulated conditions under Yucca Mountain where the US waste repository is expected to be built. They found that the corrosion level of stainless steel, used in storage canisters, was ‘severe’ due to chemical reactions being accelerated by nuclear waste […]

via US At Risk of Ecological Disaster Due to Improperly Stored Nuclear Waste, New Study Finds

Biolab for “Most Dangerous Pathogens on Earth” Opened in Wuhan Before Outbreak

Quote

biolab-tmu-700x379

/

Source – naturalblaze.com

“…In May of 2019, less than a year before the outbreak began, the U.S. Centers for Disease Control and Prevention (CDC) issued a press release that gave an overview of the projects that the new lab was currently working on. The projects included SARS, Ebola, Hemorrhagic fever, Lassa fever, avian influenza A(H5N1), Rift Valley fever, and others”

Biolab for “Most Dangerous Pathogens on Earth” Opened in Wuhan Before Outbreak – By John Vibes

As of Thursday afternoon, 23 million people in seven Chinese cities have been placed on quarantine due to the sudden outbreak of a deadly SARS-like virus called 2019-nCoV.

The illness is said to have originated in a seafood market in Wuhan and quickly spread to other areas of China, then Japan, Thailand, South Korea, and the United States. Suspected cases have been reported in Australia and Scotland. However, it is possible that there is more to the story as Chinese authorities have been running a censorship campaign to prevent the spread of information about the virus that deviates from official statements.

[…]

One very strange coincidence in the development of this outbreak is the fact that a new biolab, tasked with studying the most dangerous pathogens on earth, recently began operating in Wuhan, where the illness is said to have originated.

Back in 2017, just before experiments at the lab began, the prestigious science journal Nature published an article expressing concerns about pathogens escaping from the new Wuhan lab. The laboratory is a biosafety level-4 (BSL-4) facility, which is the highest level of biocontainment. BSL-4 facilities must meet rigid standards for decontaminating the area as well as workers after every experiment. However, BSL-4 labs remain extremely controversial because critics argue that these measures may not be enough to prevent a virus from escaping.

According to Richard Ebright, a molecular biologist at Rutgers University in Piscataway, New Jersey, the SARS virus has escaped from high-level containment facilities in Beijing multiple times.

In May of 2019, less than a year before the outbreak began, the U.S. Centers for Disease Control and Prevention (CDC) issued a press release that gave an overview of the projects that the new lab was currently working on. The projects included SARS, Ebola, Hemorrhagic fever, Lassa fever, avian influenza A(H5N1), Rift Valley fever, and others.

Scientists have examined the genetic code of the new virus and have found that it is more closely related to SARS than any other human coronavirus. In BSL-4 labs, researchers can tweak or combine deadly viruses to create mutated strains of the original illness. A 2013 report in Nature indicated that scientists in China were creating hybrid viruses in labs.

“A team of scientists in China has created hybrid viruses by mixing genes from H5N1 and the H1N1 strain behind the 2009 swine flu pandemic, and showed that some of the hybrids can spread through the air between guinea pigs,” the article revealed.

The results of the hybrid virus experiment were published in the journal Science […]

via COVER-UP: Biolab for “Most Dangerous Pathogens on Earth” Opened in Wuhan Before Outbreak – By John Vibes

Anti-Meat Lobby Tries to Suppress Rival Research Findings

Quote

medical_journal_district_at
By Donna Laframboise | Big Picture News | January 27, 2020

Much scientific research is now conducted by tribes. Some tribes think certain foods are good for us. Eggs, fat, coffee, dairy, whatever. Other tribes insist their own research shows the opposite.

The Journal of the American Medical Association (JAMA) has just published a shocking account of how the ‘eat red meat sparingly’ tribe tried to make research by a rival tribe disappear.

Last fall, a collection of systematic reviews were published by a prominent journal, the Annals of Internal Medicine (see here, here, here, here, and here). Online publication happened on October 1st, prior to the material appearing in the printed journal in mid-November.

After carefully reviewing scientific evidence concerning meat consumption, the PhDs and medical doctors involved formulated a clinical guideline, aka a nutritional recommendation, which was published at the same time. This was intended to help practicing doctors provide appropriate advice to their patients.

The short version is that most of these researchers (11 votes to 3), believe no reliable evidence justifies telling adults to eat less red meat and less processed meat. As this commentary explains, nutritional research is typically “shaky.” Studies that identify a link between meat consumption and a particular disease usually show tiny increases in risk.

The Annals had taken into account the feedback of peer reviewers both pro and con, and had made its call. To quote editor-in-chief Christine Laine, “the public should know we don’t have great information on diet.”

The JAMA article tells us that, as the Annals was preparing to publish this material online, the anti-meat tribe began mobilizing. An estimated 2,000 vitriolic e-mails flooded into Laine’s inbox during a half-hour period.

Members of an organization called the True Health Initiative contacted her at least twice. They complained about the wording of a press release the journal was circulating about the upcoming research. They also urged her to “preemptively retract publication of these papers” for “the sake of public understanding and public health” (read their letter here).

How did these people react when their outrageous attempts to suppress scientific results failed? Did they start behaving like grownups? Hardly. Instead, they complained to an agency of the US government, the Federal Trade Commission. You can read about that here in their own words.

The anti-meat tribe thinks a government body tasked with ensuring marketplace competition and fair business practices should be second-guessing medical journals. Arguing that the journal’s press release amounted to misleading advertising, their petition asked the Trade Commission to:

permanently prohibit [the Annals of Internal Medicine] from disseminating, or causing the dissemination of the advertisement at issue and require [the journal] to issue a public retraction and corrective statement regarding the advertisement. [bold added]

When that went nowhere, did these people finally start behaving in a civilized manner? I’m afraid not. Their next stop was the Philadelphia district attorney’s office. You know, the prosecutors and detectives tasked with keeping citizens safe from criminals. (The Annals offices are in Philadelphia.)

In their own press release, the anti-meat tribe said the Annals should be investigated for “potential reckless endangerment.” The journal, they insisted, had distributed “dangerous and misleading information.”

The entity that turned first to the Trade Commission and then to the criminal justice system calls itself the Physicians Committee for Responsible Medicine. It’s unofficial motto is: if you can’t persuade people to do what you want, find a third party who’ll compel them to do so. Just kidding. It actually sees itself as leading a “revolution” – based on the idea that plant-based diets “can prevent and even reverse diabetes, heart disease, and high blood pressure.”

This is a lobby group, an activist organization. According to its own website, only 12,000 of its 175,000 members (7%) are actually physicians […]

 

via Cancel Culture Hits Medical Journals